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  5. Timothy Burns, M.D., Ph.D.
Timothy Burns, M.D., Ph.D.

Timothy Burns, M.D., Ph.D.

University of Pittsburgh

Research Project:
Determining How Two Genes Interact in Lung Cancer

Research Topic:

  • gene expression transcription

Research Disease:

  • lung cancer

Recent advances in the treatment of lung cancer have confirmed that the disease is not a single disease entity but rather a collection of distinct cancers driven by cancer genes called oncogenes which cause the tumors to grow. This knowledge has led to the development of targeted therapies for a percentage of patients. One important oncogene, c-MET, is required for a tumor to grow while another gene, TWIST 1, has been shown to regulate the c-MET gene. This study will determine how these two genes interact and how drugs may modulate their activity.

Page last updated: June 7, 2024

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