Donate
Call the Lung HelpLine
Ask a Question
The following text field filters the results that follow as you type. Use Tab to access the results.
  1. Home
  2. Research & Reports
  3. About Our Research
  4. Previously Funded Researchers
  5. Patrick Link, PhD
Patrick Link, PhD

Patrick Link, PhD

Mayo Clinic

Research Project:
Myeloperoxidase Promotes Persistent Fibrosis

Grant Awarded:

  • Dalsemer Grant

Research Topic:

  • basic biologic mechanisms

Research Diseases:

  • interstitial lung disease
  • pulmonary fibrosis

Pulmonary fibrosis (PF) is a progressive fatal lung disease expected to increase dramatically due to post-COVID complications. In human disease and experimental models, it remains unclear what separates normal wound healing from progressive lung scarring and persistent disease. An enzyme called myeloperoxidase increases in PF and has been correlated with rapid deterioration of pulmonary fibrosis patients. Myeloperoxidase contributes to fibrosis in other major organ systems as well. Whether myeloperoxidase contributes to PF progression and prevents resorption of scar tissue is unknown. We will use laboratory tests and animal models of PF to determine the role of this enzyme in PF and determine if it is a potential target for treatment.

Page last updated: October 3, 2023

Implementation and Interpretation of Spirometry
Belgrade, MT | Dec 05, 2024 Freedom From Smoking Clinic
Manchester, CT | Jan 06, 2025
See All Events